After a polypeptide is produced in protein synthesis, it's not necessarily a functional protein yet! Explore protein folding that occurs within levels of protein structure with the Amoeba Sisters! Primary, secondary, tertiary, and quaternary protein structure levels are briefly discussed. Video also mentions chaperonins (chaperone proteins) and how proteins can be denatured.

Table of Contents:
00:00 Intro
0:41 Reminder of Protein Roles
1:06 Modifications of Proteins
1:25 Importance of Shape for Proteins
1:56 Levels of Protein Structure
2:06 Primary Structure
3:10 Secondary Structure
3:45 Tertiary Structure
4:58 Quaternary Structure [not in all proteins]
6:01 Proteins often have help in folding [introduces chaperonins]
6:40 Denaturing Proteins

*Further Reading Suggestions*

Related to Protein Misfoldings:

https://www.nature.com/scitable/topicpage/protein-misfolding-and-degenerative-diseases-14434929
https://www.scientificamerican.com/article/misfolded-proteins-travel-in-huntington-s-disease/

Learn About "The Protein Folding Problem":
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443096/


Factual References:

OpenStax, Biology. OpenStax CNX. Jun 1, 2018 http://cnx.org/contents/185cbf87-c72e-48f5-b51e-f14f21b5eabd@11.2.

Reece, J. B., & Campbell, N. A. (2011). Campbell biology. Boston: Benjamin Cummings / Pearson.


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